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Jellyfish are marine invertebrates belonging to the Scyphozoan class, and in turn the phylum Cnidaria. The body of an adult jellyfish is composed of a bell-shaped, jelly producing substance enclosing its internal structure, from which the creature's tentacles are suspended. Each tentacle is covered with stinging cells (cnidocytes) that can sting or kill other animals: most jellyfish use them to secure prey or as a defense mechanism. Others, such as Rhizostomae, do not have tentacles at all. To compensate for its lack of basic sensory organs and a brain, the jellyfish exploits its nervous system and rhopalia to perceive stimuli, such as light or odor, and orchestrate expedient responses. In its adult form, it is composed of 94–98% water and can be found in every ocean in the world. Most jellyfish are passive drifters that feed on small fish and zooplankton that become caught in their tentacles. Jellyfish have an incomplete digestive system, meaning that the same orifice is used for both food intake and waste expulsion. They are made up of a layer of epidermis, gastrodermis, and a thick layer called mesoglea that actually produces a main part of jelly and it separates the epidermis from the gastrodermis.

Their shape is not hydrodynamic, which makes them slow swimmers but this is little hindrance as they feed on plankton, needing only to drift slowly through the water. It is more important for them that their movements create a current where the water (which contains their food) is being forced within reach of their tentacles. They accomplish this by rhythmically opening and closing their bell-like body.

Since jellyfish do not biologically qualify as actual "fish", the term "jellyfish" is considered a misnomer by some, who instead employ the names "jellies" or "sea jellies". The name "jellyfish" is also often used to denote either Hydrozoa or the box jellyfish, Cubozoa. The class name Scyphozoa comes from the Greek word skyphos, denoting a kind of drinking cup and alluding to the cup shape of the animal.

Most jellyfish pass through two different body forms during their life cycle. The first is the polyp stage; in this phase, the jellyfish takes the form of either a sessile stalk which catches passing food, or a similar free-floating configuration. The polyp's mouth and tentacles are located anteriorly, facing upwards.

In the second stage, the jellyfish is known as a medusa. Medusae have a radially symmetric, umbrella-shaped body called a bell. The medusa's tentacles hang from the border of the bell.

Jellyfish are dioecious (that is, they are either male or female). In most cases, to reproduce, a male releases his sperm into the surrounding water. The sperm then swims into the mouth of the female jelly, allowing the fertilization of the ova process to begin. Moon jellies, however, use a different process: their eggs become lodged in pits on the oral arms, which form a temporary brood chamber to accommodate fertilization.

After fertilization and initial growth, a larval form, called the planula, develops from the egg. The planula larva is small and covered with cilia. It settles onto a firm surface and develops into a polyp. The polyp is cup-shaped with tentacles surrounding a single orifice, perhaps resembling a tiny sea anemone. Once the polyp begins reproducing asexually by budding, it's called a segmenting polyp, or a scyphistoma. New scyphistomae may be produced by budding or new, immature jellies called ephyra may be formed. Many jellyfish can bud off new medusae directly from the medusan stage.

Most jellyfish do not live longer than six months, 2 and a half months being more common.

Most jellyfish have tentacles or oral arms coated with thousands of microscopic nematocysts; generally, each of these nematocyst has a "trigger" (cnidocil) paired with a capsule containing a coiled stinging filament, as well as barbs on the exterior. Upon contact, the filament will swiftly unwind, launch into the target, and inject toxins. It can then pull the victim into its mouth, if appropriate.

Although most jellyfish are not perniciously dangerous to humans, a few are highly toxic, such as Cyanea capillata. The recently discovered Carukia barnesi is also suspected of causing two deaths in Australia. Contrary to popular belief, the menacingly infamous Portuguese Man o' War (Physalia) is not actually a jellyfish, but a colony of hydrozoan polyps. Regardless of the acutal toxicity of the stings, many victims find them very painful, and some individuals may have severe allergies similar to bee stings.

A jellyfish can detect the touch of other animals using a nervous system called a "nerve net", which is found in its epidermis. Impulses to the nerve cells are sent from nerve rings that have collected information from the environment of the jellyfish through the rhopalial lappet, which is located around the animal's body. Jellyfish also have ocelli that cannot form images, but are sensitive to light; the jellyfish can use these to determine up from down, basing its judgement on sunlight shining on the surface of the water.

Jellyfish do not have a specialized digestive system, osmoregulatory system, central nervous system, respiratory system, or circulatory system. They are able to digest with the help of the gastrodermis that lines the gastrovascular cavity, where nutrients from their food are absorbed. They do not need a respiratory system since their skin is thin enough that oxygen can easily diffuse in and out of their bodies. Jellyfish have limited control over their movement and mostly free-float, but can use a hydrostatic skeleton that controls the water pouch in their body to actuate vertical movement.

In cell biology, ectoplasm ("outer plasma") refers to the outer regions of jelly fish. The jelly like material called (ectoplasma or plassy for short) typically contains a smaller amount of protein granules and other organic compounds than inner cytoplasm, also referred to as endoplasm.

A group of jellyfish is often called a "smack." Many species of jellyfish are also capable of congregating into large swarms or "blooms" consisting of hundreds or even thousands of individuals. The formation of these blooms is a complex process that depends on ocean currents, nutrients, temperature and oxygen content. Jellyfish will sometimes mass breed during blooms. Jellyfish population is reportedly raising major ecological concerns for a possible jellyfish outbreak.